Analyse von Zellfunktionen mit Hochdurchsatz-Mikroskopie und KI

Abstract

Genes that share a distinct phenotype often share biological functions. A principle that is used in genetic screens and that provides the basis for our understanding of key biological processes. Traditionally, individual
phenotypes were used to group mutant alleles into cellular pathways. Today, high-throughput technologies allow the screening of thousands of perturbations. Using computational methods and machine learning, millions of images are profiled to assign biological effects to genes and drugs.

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