Bäckerhefe Saccharomyces cerevisiae als universelle chemische Mikrofabrik


One of the applications of the emerging synthetic biology field is the
enzymatic production of chemicals, either by individual enzymes or by
cascades of whole metabolic pathways. Here, the discovery of novel
metabolites from baker’s yeast transformed with yeast artificial chromosomes
is described. One particular class of compounds found repeatedly
are structurally diverse novel polyketides obtained by expression of mixes
of PKSIII (polyketide synthase type III).

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