Biowissenschaftliche Anwendungen der Quartzkristall­-Mikrowaage

Abstract

Biomolecular interactions can be measured either in solution or on sur­faces. The quartz crystal microbalance (QCM) is a mechanical biosen­sor, and interactions of biomolecues with a large variety of different
surfaces are measured through changes in the resonant frequency of a quartz sensor. The QCM findsapplications in cases when not only the affinityof a given biomolecular interaction is to be measured, but also accompanying changes in conformation or mechanical properties.