Chirale Epoxidierung von Aryl-Alkyl-Ethern aus Lignin

Abstract

Processing of lignin provides access to mono-aromatic compounds with a
styrene-like structure. The vinyl sidechain can be attacked by monooxy -
genases, such as styrene or indole monooxygenases, to yield enantiopure
epoxides. The obtained epoxides can be converted into valuable products,
either enzyme- or non-enzyme driven. This provides access to drug-like
molecules and technically relevant synthesis precursors. Herein, we
report the setup of a simple screening strategy for useful epoxidases.