Cytochrome P450 – vielseitige Enzyme für Medizin und Biotechnologie

Abstract

Cytochromes P450 are heme containing enzymes that catalyze numerous
oxidation reactions including hydroxylation of non-activated CH-bonds,
epoxidation, dealkylation and even C-C bond cleavage. Along with their
broad substrate spectrum, P450s often possess high regio-, chemo-, and
stereoselectivity, thereby playing an essential role in metabolism. Due to
their versatility P450s are the rising stars in biotechnological applications
and synthetic biology.