Das stressige Leben des Bacillus subtilis


Here we present Bacillus subtilis as a model system to study protein
homeostasis and protein quality control in conjunction with the different
layers of its stress response systems. We established a new marker to
study protein aggregation in vivo. Furthermore, we observed that the
transcription factor Spx, which has already been characterized as a
central player to activate transcription of redox-chaperones during heat
shock and oxidative stress response, was also able to simultaneously
inhibit the transcription of translation-related genes as a second
response to stress.