Dynamische Peptidvesikel als Vorstufe synthetischer Zellen?

Abstract

Compartmentalization and spatial control of biochemical reactions are essential for the creation of artificial cellular systems. But it is notoriously difficult to implement reaction networks and membrane building blocks in vitro. In this article, we briefly highlight our work on the formation of peptide-based vesicles as artificial cell precursors with a size of up to 100 μm. These cell mimics are able to produce RNA aptamers and proteins at the inside, and are further capable of strong growth.

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