Eine rekombinante Produktionsplattform für Peptide

Abstract

The production of peptides as active pharmaceutical ingredients (APIs) by recombinant technologies is of emerging interest. A reliable production platform, however, is still missing due to inherent peptide characteristics such as proteolytic sensitivity, aggregation, and cytotoxicity. We developed a new approach – NumaswitchTM. It solves present limitations and provides a cost-efficient production platform for diverse peptides and hard-to-be-expressed proteins.

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