Klein, gefährlich und gesprächig – Quorum sensing bei Vibrio cholerae


To efficiently interact with their environment, bacteria often work in
groups to solve complex tasks. Coordination of collective functions
requires communication among the members of the group, a process
typically referred to as quorum sensing (QS). Marine Vibrio species,
including the major human pathogen Vibrio cholerae, have become a
model to study the regulatory architecture underlying QS. In this
review we summarize how V. cholerae employs QS to regulate viru-
lence, biofilm formation, type-6-secretion, and phage interactions.