Lichtsignale für die Hefe


Natural photoreceptors from plants and microorganisms are used for
synthetic approaches to control cell behaviour. Light perception by the
photoreceptor, often by a cofactor, induces a conformational change,
which is transduced to the effector and regulates its activity. Synthetic
combinations of photoreceptors and effectors resulted in a wealth of
cellular events that are controlled by optogenetic tools. A general
approach is to regulate protein abundance controlling either protein
stability, protein biosynthesis or both with optogenetic tools.