Makrophagen in der Krankheitsentstehung und Therapie

Abstract

Macrophages are unique cells of the innate immunity and can be found in various tissues (tissue resident macrophages; TRMs). Macrophagesand TRMs play a pivotal role in tissue homeostasis and can contribute to the onset and progression of certain diseases. We and others have developed macrophage-based cellular immunotherapies and explored the field of immune cell farming using induced pluripotent stem cells (iPSCs). Combination of iPSCs and bioreactors opens new ways in cellular therapies.

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