Miniaturisierung von diagnostischen point-of-care-Plattformen

Abstract

Molecular point-of-care (POC) testing is defined as the diagnostic testing
of acute-care parameters at or close to the patients „bed side“ [1]. The
development of POC technologies and platforms aims to speed up diagnosis
time to start targeted therapeutic treatments without a lag in time
caused by the transport of samples to external laboratories as well as
lengthy analytical methods. This article describes an enabling approach
based on reversed purification of nucleic acids resulting in a fast sample
analysis and a miniaturized disposable sample cartridge.