RNA-basierte Kontrollmechanismen der Yersinia-Virulenz


Enteropathogenic Yersiniae evolved a plethora of virulence traits
which allow them to colonize the intestine and gut-associated lymphatic tissues of mammals. In these host niches they have to tightly adjust the expression of required pathogenicity factors to resist
attacks by the host immune system. Here, we present how enteric Yersiniae use intricate control networks which include numerous
regulatory and sensory RNAs, RNA-binding proteins and RNases to control their virulence attributes.