Stoffwechsel 2.0: Retrosynthese des mikrobiellen Metabolismus

Abstract

VAAM-Forschungspreis 2017
Synthetic biology is a fast growing field with big promise for biotechnological
applications. In our laboratory, we aim at realizing synthetic
metabolism in a truly de novo approach via metabolic retrosynthesis. This
includes the discovery and engineering of novel enzymes to sustain our
designer pathways, the in vitro reconstitution and optimization of the synthetic
routes, as well as the transplantation of these artificial pathways
into living organisms.

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