Visualisierung von Mutationen auf Einzelzellebene

Abstract

Bacterial mutations have been investigated since many years, but they
remain difficult to observe directly in single cells, which limits the
analysis of the underlying molecular mechanism. However, for the
investigation of mutations at the level of single cells, precise analytical
tools are currently developed. This article describes a workflow for
visualizing mutations in single cells and lays the foundation for the
quantification of bacterial mutation rates in the future.

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