Wie Zellen kommunizieren: extrazelluläre Vesikel als Signalübermittler


Development and homeostasis of multicellular organisms requires a constant exchange of information. Intercellular communication can be mediated by extracellular vesicles – tightly packed informational units that are secreted by virtually all cell types. Depending on their origin they carry distinct sets of proteins and RNAs and elicit diverse signal­ling responses in close and distant target cells. Despite their crucial role for health and disease, their biogenesis remains poorly understood.