Zellen beim Wachsen und Sterben zuschauen – Tumorzellmodelle in 2D und 3D


Image-based analysis of cellular proliferation in 2D and 3D cultures is a
great tool to gain insights in influences of potential new drugs or the relevance
of novel therapeutic targets. Multiplex assays can be performed to
simultaneously determine the total number of cells and the number of
dead, apoptotic or live cells without intervention like trypsinisation of
cells or dissociation of spheroids. Here, we give a short introduction to
the image-based screening of 2D and 3D cultures.